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Encouraging Initial Response of Restless Legs Syndrome to Pramipexole
Neurol 51:1221-123, Becker,P.M.,et al, 1998
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Article Abstract
Restless legs syndrome (RLS) is a common condition that results in uncomfortable sensations and an urge to move the limbs. Two centers tested a new dopamine agonist, pramipexole, in 23 patients with RLS in a time-limited, open-label, clinical trial. After 4 weeks or more, 19 patients reported significant improvement as assessed by the short International Restless Legs Syndrome Study Group questionnaire (p < 0.0001). These encouraging preliminary results justify larger, controlled trials for pramipexole in patients with RLS.
 
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dopamine agonist
movement disorder
movement disorder,treatment of
pramipexole
restless leg syndrome
treatment of neurologic disorder

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